Composition
Each 600 mg Capsules contains extract
Commiphora molmol (Heerabol) Oleoresin……………….250 mg
Gardenia gummifera (Naadihingu) Gum resin ……….....83 mg
Tagates erecta (Genda) Flowers…………………………83.5 mg
Mesua ferrea (Nagakesar) Stem…………………………83.5 mg
Turbinella pyrum ( Shankhi ext.)…………………………….20 mg
Azadirachta indica ( Nimboli Extract) …………………… 20 mg
Triphala Ass …………………………………………………...20 mg
Arshukuthar Ras Ass. …………………………………………20 mg
Arshoghani Vati Ass. ………………………………………….20 mg
(Standardized to contain not less than 7% catechins and epicatechins)
Approval:
FisoHeal formulation is approved by the licensing authority of AYUSH.
Description:
Commiphora molmol is small perennial tropical trees that grown in arid and semiarid regions in East Africa, Saudi Arabia, and India. Myrrh is a resinous exudate (oleo-gum resin) obtained from the stem of C. molmol trees. Myrrh has been approved by USFDA as a safe natural flavoring agent in foods and beverages and as fragrance in cosmetics. For many years, myrrh (oleo-gum resin) has been used for healing wound injuries. [1]
2. Gardenia gummifera (Naadihingu)
Nadi hingu- Gardenia gummifera is an herb mentioned in the ayurvedic pharmacopoeia for the treatment of fever, digestive disorders, dental problems during eruption, wounds, skin diseases and pain in abdomen due to intestinal worm or constipation. The plant grows all over India, in deciduous forests, especially in Maharashtra, Gujarat, Bihar and South India. [3, 4]
3. Tagates erecta (Genda Flowers)
Tagetes erecta, popularly known as marigold, is grown as an ornamental plant. Flowers of this plant are used loose or in garlands for social and religious purposes in Eastern countries (India).
In traditional and homeopathic medicine flower leaves has been used for skin complaints, wounds and burns, conjunctivitis and poor eyesight, menstrual irregularities, varicose veins, hemorrhoids, duodenal ulcers, etc.
4. Mesua ferrea (Nagakesar) Stem
Nagakesara (Mesua ferrea Linn.) has its special place in Ayurveda as the drug is useful for multi system disorders and this drug happens to be most consumed drug by domestic industries in volumes (million tons) after Amalaki and Hareetaki. [8]
The chemical properties of Turbinella pyrum (the Indian chank shell) include calcium carbonate, calcium nitrates, and calcium phosphates. The shell is also made of aragonite, which can be converted to calcite.
Chemical composition
Other chemical properties
Triphala Ass.
Herbal remedies are among the most ancient medicines used in traditional systems of healthcare such as Ayurveda. Triphala, a well-recognized and highly efficacious polyherbal Ayurvedic medicine consisting of fruits of the plant species Emblica officinalis (Amalaki), Terminalia bellerica (Bibhitaki), and Terminalia chebula (Haritaki), is a cornerstone of gastrointestinal and rejuvenative treatment. Triphala is classified as a tridoshic rasayana, meaning that the energetics are appropriate for Vata, Pitta, and Kapha or all types of patients. Charak describes rasayanas as having the qualities of supporting strength and immunity.1
Azadirachta indica (Nimboli extract)
Neem (Azadirachta indica) is a member of the Meliaceae family and its role as health-promoting effect is attributed because it is rich source of antioxidant. It has been widely used in Chinese, Ayurvedic, and Unani medicines worldwide especially in Indian Subcontinent in the treatment and prevention of various diseases. Earlier finding confirmed that neem and its constituents play role in the scavenging of free radical generation and prevention of disease pathogenesis. The studies based on animal model established that neem and its chief constituents play pivotal role in anticancer management through the modulation of various molecular pathways including p53, pTEN, NF-κB, PI3K/Akt, Bcl-2, and VEGF. It is considered as safe medicinal plants and modulates the numerous biological processes without any adverse effect. In this review, I summarize the role of Azadirachta indica in the prevention and treatment of diseases via the regulation of various biological and physiological pathways.
Azadirachta indica (Neem) is used for piles treatment due to its antimicrobial, anti-inflammatory, and astringent properties, helping to relieve pain, reduce inflammation, and promote healing.
Arshakuthar Ras Ass.
Arshakuthar Ras is a combination of kajjali, lauha bhasma, shunthi, tamra bhasma, danti mool, marica, pippali, surana, vamsha, shuddha tankana, yavakshar, saindhava lavana. Arsh Kuthar Ras Tablet is used in the management of haemorrhoids (piles). Piles (haemorrhoids) are swellings that develop inside and around the back passage (anus). Symptoms range from temporary and mild, to persistent and painful.
Arshakuthar Ras is a time-tested clinically proven classical Ayurvedic formulation in tablet form. It is a herbal-mineral combination, extremely beneficial in piles, fissures and fistula. Especially effective to help alleviate pricking and burning sensation of anal region.
9. Arshoghani Vati Ass.
Arshoghni Vati contains various medicinal properties such as anti-hemorrhoid (agents used to treat piles), carminative (agents expel outgas from the stomach), blood purifier, anti-constipation, and hemostatic (agents that check bleedings).
Arshoghni Vati is an ayurvedic and herbal medicine. It is accessible in a tablet structure and it is to be taken orally. Vati is known as pills manufactured by diminishing the decoction of herbs used to a thick thickness and after that pouring a resin exudate for making a pill mass that is effective in arresting the bleeding and non-bleeding types of piles along with easy bowels, reducing chances of constipation.
Arshoghni Vati is an ayurvedic medicine used for treating all types of hemorrhoids. It is very common and is beneficial in the treatment of both bleeding and non-bleeding piles. Arshoghini Vati is mainly effective for treating bleeding piles. It stops bleeding within 1 to 3 days of its regular use.
Arshoghni Vati has Ayurvedic herbs that reduce discomfort, bleeding occurring during bowel movement, itching and irritation in the anorectal region. It reduces venous swelling and size of the pile lump.
Arshoghni Vati shrinks pile mass, controls bleeding and heals inflamed skin and the mucus membrane. The nearby or local pain-relieving property of arshoghni vati guarantees torment-free fecal discharge and furthermore goes about as an antimicrobial and forestalls auxiliary microbial contaminations in the body. The drug offers symptomatic relief from its tridosha pacifying action and has the following medicinal uses:
Mechanism of action of FisoHeal
Hemorrhoids are defined as the symptomatic enlargement and distal displacement of the normal anal cushions. [14]
The most common symptom of hemorrhoids is rectal bleeding associated with bowel movement. The abnormal dilatation and distortion of the vascular channel, together with destructive changes in the supporting connective tissue within the anal cushion, is a paramount finding of hemorrhoids. The dysregulation of the vascular tone and vascular hyperplasia might play an important role in hemorrhoidal development. [14]
FisoHeal is a venotonic drug and a vascular-protecting agent. The efficacy of FisoHeal is accounted for by its specific action on the principal elements of venous disease.
Venotonic: FisoHeal reinforces venous tone, decreases venous capacitance, venous distensibility and venous emptying time.[15]
Vascular-protecting agent: FisoHeal protects the microcirculation by fighting the microcirculation-damaging process; it combats venous inflammation by decreasing leukocyte activation, and as a consequence, by inhibiting the release of inflammatory mediators (Cytokines, IL 1-β & TNFα), principally free radicals (5-LOX, ROS & RNS) and prostaglandins. Thus, FisoHeal normalizes capillary permeability and strengthens capillary resistance.[15]
FisoHeal acts on the lymphatic system: It improves lymphatic drainage by increasing lymph flow and lymph oncotic pressure. This action on the lymphatic system associated with a venotonic and vasculoprotective effect, explains the activity of FisoHeal on edema.[15]
By virtue of its venotonic, vascular-protecting and anti-inflammatory action, FisoHeal improves hemorrhoidal symptoms and signs e.g., anal discomfort, pain, redness, anal discharge, tenesmus, pruritus, erythema and bleeding. It also significantly reduces the frequency, severity and duration of acute hemorrhoidal attacks and bleeding by chronic treatment in all grades of haemorrhoids.[16]
USAGE
FisoHeal capsules are used for the treatment of hemorrhoids (piles) and anal fissure
Dosage and Administration
Two capsules twice a day for 15 days every month for 3 months.
Heavy metal analysis of FisoHeal revealed the levels of arsenic, lead, cadmium and mercury within the normal limit
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